Associação do sono com sintomas de ansiedade e depressão em indivíduos com doença pulmonar obstrutiva crônica
Association of sleep with symptoms of anxiety and depression in individuals with chronic obstructive pulmonary disease
Elis Moraes Martins, Daniele Dala Pola, Thaiuana Maia Ferreira, Letícia Yumi Ogochi, Maria Gabriela Fernandes, Ana Lívia Trindade, Giovanna Alves, Raquel Hirata, Fabio Pitta
Resumo
Introdução: A doença pulmonar obstrutiva crônica (DPOC) é uma doença essencialmente respiratória, mas com repercussões extrapulmonares, como comprometimento do sono e sintomas de ansiedade e depressão. Apesar da relevância do sono na DPOC, pesquisas prévias da sua associação com a saúde mental focaram apenas em indivíduos hospitalizados, carecendo de investigações em condições estáveis. Objetivo: Correlacionar a qualidade do sono avaliado subjetivamente e objetivamente com níveis de ansiedade e depressão em indivíduos com DPOC estável e investigar a influência das características do sono sobre esses sintomas nessa população. Métodos: Neste estudo transversal, os indivíduos foram submetidos à espirometria, rastreio de sintomas de ansiedade e depressão pela Escala Hospitalar de Ansiedade e Depressão (HADS), avaliação da qualidade do sono subjetivo pelo Índice de Qualidade do Sono de Pittsburgh (PSQI) e mensuração do sono objetivo por actígrafo. Para análise estatística utilizou-se os testes de Shapiro-Wilk, coeficiente de Spearman e regressão linear simples com um p<0,05 representando significância estatística. Resultados: Estudou-se 36 indivíduos com diagnóstico de DPOC. Encontrou-se correlações moderadas do PSQI com a escala HADS domínio ansiedade e depressão. A regressão linear simples mostrou que o PSQI é influenciado pela escala HADS. Não foi encontrada correlação significativa entre a escala HADS e variáveis de sono avaliado objetivamente. Conclusão: Em indivíduos com DPOC estável, a qualidade do sono avaliado subjetivamente correlacionou-se moderadamente com sintomas de ansiedade e depressão, assim como há relação de influência entre essas variáveis. Entretanto, não há correlação entre o sono avaliado objetivamente e sintomas de ansiedade e depressão nessa população.
Palavras-chave
Abstract
Background: Chronic obstructive pulmonary disease (COPD) is primarily a respiratory condition, although it also presents extrapulmonary effects such as sleep disturbances and symptoms of anxiety and depression. Although sleep plays a crucial role in COPD, previous research on its association with mental health has focused mainly on hospitalized patients, with few studies examining individuals in stable conditions. Aim: To correlate subjectively and objectively assessed sleep quality with levels of anxiety and depression in individuals with stable COPD, and to investigate how sleep characteristics influence these symptoms in this population. Methods: In this cross-sectional study, participants underwent the following assessments: spirometry; screening for anxiety and depression symptoms using the Hospital Anxiety and Depression Scale (HADS); subjective sleep quality assessment using the Pittsburgh Sleep Quality Index (PSQI); and objective sleep measurement with actigraphy. Statistical analyses included the Shapiro–Wilk test, Spearman’s correlation coefficient and simple linear regression. A p-value < 0.05 was considered statistically significant. Results: A total of 36 individuals diagnosed with COPD were evaluated. Moderate correlations were observed between PSQI scores and both the anxiety and depression domains of the HADS. Simple linear regression indicated that PSQI scores were influenced by HADS results. No significant correlations were found between HADS scores and objectively measured sleep variables. Conclusion: In individuals with stable COPD, subjectively assessed sleep quality showed a moderate correlation with symptoms of anxiety and depression, suggesting an interdependent relationship between these variables. However, no association was found between objectively measured sleep and symptoms of anxiety and depression in this population.
Keywords
Referências
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Submetido em:
22/01/2025
Aceito em:
27/12/2025
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